A new era of nanofiber membranes-Innovation breakthroughs by WECHANGE

After three years of research and development, the R&D team of WECHANGE Technology has successfully overcome the key manufacturing technologies of nanofiber liquid sterilization filtration membranes and filter elements, and developed ethylene vinyl alcohol copolymer (EVOH) nanofiber liquid sterilization filtration membranes (hereinafter referred to as EVOH sterilization membranes), syringe filters, and pleated filter products.
　　WECHANGE has basically completed the core validation of the sterilization membrane and is gradually carrying out the sterilization process validation work for pharmaceutical and food enterprises. This breakthrough not only marks a new level of filtration technology strength in the field of biomanufacturing but also brings revolutionary solutions to the pharmaceutical and food industries.
　　Two specifications of EVOH sterilization membranes have been developed this time: a 0.22 μ m pharmaceutical sterilization membrane (with an average pore size of 120nm) and a 0.45 μ m food sterilization membrane (with an average pore size of 410nm), tailored for pharmaceutical and food production processes, respectively. In addition, customized sterilization membrane products with other pore sizes can be also developed according to the special needs of customers. Compared to existing polymer microporous filtration membranes such as polyethersulfone (PES), EVOH sterilization membranes possess the following merits:
　　(1) The intrinsic hydrophilic feature facilitates the infiltration of medicinal and food solutions, and are not easily adhered with organic substances such as proteins.
　　(2) Derived from fiber stacking, Irregular pores are formed with anisotropic channels and high porosity, which not only intercept microorganisms, but also provide more transport space for fluids. The pores are not easily blocked, which can significantly improve the filtration flux.
　　(3) The dense accumulation of fibers and higher uniformity of pore size are conducive to the absolute interception of bacteria.
　　(4) The manufacturing of nanofiber membranes is physical process without residual organic solvents and precipitation, which is conducive to ensuring the purity of drugs and food.
　　With the increasing global attention to medical health and food safety, the market demand for sterilization membranes is constantly growing. The new product of Wuhan WECHANGE Technology Co., Ltd. provides a new choice for the international and domestic sterilization and filtration markets.
　　It is reported that the liquid virus removal membrane developed based on nanofiber membrane manufacturing technology is also in the process of promotion and is expected to achieve small-scale manufacturing within 2024. The company will continue to increase research and development investment, promote the transformation of more technological achievements, and provide downstream customers with safer and more efficient products and services.